New technologies are dramatically changing human civilization in a way few could have imagined even at the end of the 20th century. And yet, many things will change even more. Very soon, computer intelligence will surpass the abilities of the human brain, genetic research and regenerative medicine will create practically immortal genetically enhanced humans with super-intelligence and superpowers, and natural people will become a minority in the world of human cyborgs. In such a new world, the supremacy of humans will be disputed. This paper presents the issues arising from the mind controlled devices, pointing out those viewpoints which might completely destroy, and those which can preserve the equilibrium of the world we live in.